As long as Adanto Vanguard is attacking, it gets +2/+0.
Pay 4 life: Adanto Vanguard gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
1 /
1
{4}{W}{W}
Axis of Mortality
Enchantment
At the beginning of your upkeep, you may have two target players exchange life totals.
{B}
Blood Celebrant
Creature - Human Cleric
{B}, Pay 1 life: Add one mana of any color.
1 /
1
{3}{B}{B}
Bloodgift Demon
Creature - Demon
Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.
5 /
4
{1}{B}
Carnival of Souls
Enchantment
Whenever a creature enters the battlefield, you lose 1 life and add {B}.
{2}{W}
Cloudsteel Kirin
Artifact Creature - Equipment Kirin
Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)
3 /
2
{3}{B}
Consuming Vapors
Sorcery
Target player sacrifices a creature. You gain life equal to that creature's toughness.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)
{2}{B}
Deepwood Ghoul
Creature - Zombie
Pay 2 life: Regenerate Deepwood Ghoul.
2 /
1
{2}{B}{B}
Defiler of Flesh
Creature - Phyrexian Horror
Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.
4 /
4
{2}{W}{W}{W}
Ethereal Champion
Creature - Avatar
Pay 1 life: Prevent the next 1 damage that would be dealt to Ethereal Champion this turn.
3 /
4
{6}{B}{B}{B}
Kuro, Pitlord
Legendary Creature - Demon Spirit
At the beginning of your upkeep, sacrifice Kuro, Pitlord unless you pay {B}{B}{B}{B}.
Pay 1 life: Target creature gets -1/-1 until end of turn.
9 /
9
{4}{B}{B}
Magus of the Mirror
Creature - Human Wizard
{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.
4 /
2
{4}{B}
Marrow Bats
Creature - Bat Skeleton
Flying
Pay 4 life: Regenerate Marrow Bats.
4 /
1
{2}{W}{B}
Martyrs' Tomb
Enchantment
Pay 2 life: Prevent the next 1 damage that would be dealt to target creature this turn.
{2}{B}
Mischievous Poltergeist
Creature - Spirit
Flying
Pay 1 life: Regenerate Mischievous Poltergeist.
1 /
1
{2}{W}{W}{W}
Near-Death Experience
Enchantment
At the beginning of your upkeep, if you have exactly 1 life, you win the game.
{3}{W}{U}{B}
Oloro, Ageless Ascetic
Legendary Creature - Giant Soldier
At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.
4 /
5
{3}{B}
Pact Weapon
Artifact - Equipment
As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip--Discard a card.
{1}{B}
Pain Seer
Creature - Human Wizard
Inspired -- Whenever Pain Seer becomes untapped, reveal the top card of your library and put that card into your hand. You lose life equal to that card's mana value.
2 /
2
{6}{B}{B}{B}
Profane Transfusion
Sorcery
Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.
{5}{B}{B}
Repay in Kind
Sorcery
Each player's life total becomes the lowest life total among all players.
{4}{U}{U}
River's Rebuke
Sorcery
Return all nonland permanents target player controls to their owner's hand.
{6}
Soul Conduit
Artifact
{6}, {T}: Two target players exchange life totals.
{2}{B}
Wall of Blood
Creature - Wall
Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.