You want to fill their graves and pull their creatures from them with
The Scarab God. Four copies of
Fraying Sanity helps, but it needs cards to trigger.
Abrade can kill a creature in a pinch or destroy annoying artifacts, making it a great red card to assist in a two for one deal.
Banewhip Punisher to let you kill an annoying creature regardless of its toughness.
By force for artifact heavy decks on your sideboard.
Lethal Sting. Lilliana, Death Weilder.
Never // Return .
Violent Impact kills a land, triggers
fraying sanity.
Dispossess.
Seer of the Last Tomorrow.
Winds of Rebuke.
Doomfall.
Lay Bare the Heart.
Dreamstealer.
Nimble Obstructionist.
Torment of Hailfire.
Torment of Scarabs.
Wretched Camel. Every time a card hits their graveyard, whether from their deck, their hand or the battlefield, they lose another option (or two or more, if more than one
fraying sanity is out), so you want to flip the board as often as possible. Creatures with deathtouch are your friends, such as
wasteland scorpion. But you want their deaths tocount by taking down threats. Perhaps one of the best creature killers is
Hour of Devastation, allowing you to even take out Oketra, Hazoret, Bontu, Rhonas and Kefnet. I would definitely take
The Scorpion God over Bontu.