Deck updated to War of the Spark because in the very next set they printed The First Sliver, who completely obsoletized this deck.

Combo Lines

• cast Food Chain
• repeatedly cast and exile Misthollow Griffin/Squee, the Immortal/Eternal Scourge to Food Chain to get infinite mana
• repeatedly cast and exile Niv-Mizzet Reborn to Food Chain to browse through your library
• then you can either:
  • hit Circu, Dimir Lobotomist and cast it
  • keep looping Niv-Mizzet Reborn to exile your opponents' libraries with Circu
• or:
  • hit Jhoira, Weatherlight Captain and cast it
  • keep looping Niv-Mizzet Reborn to draw your entire deck with Jhoira
  • cast Laboratory Maniac to win the game

Personal Choices

• Xantid Swarm: it may silence target opponent during your turn repeatedly. After that, you may also exile it to Food Chain to help going off. It compares positively to Hope of Ghirapur (which doesn't belong to this deck, but is a totally legit card in cEDH).
• Riftsweeper: useful in case you've exiled all your win conditions when searching for Food Chain with any of the "forbidden" tutors (Demonic Consultation, Tainted Pact and Plunge into Darkness).

Notable Exclusions

• Manipulate Fate/Foresight/Extract: aside from tutoring for Misthollow Griffin, Squee, the Immortal and Eternal Scourge, they do nothing. Moreover, if you search for Food Chain with any of the "forbidden" tutors you're likely to hit those creatures anyway.